Erythromycin resistance in Group A Beta-hemolytic streptococci

Aim: Streptococcus pyogenes (Group A Beta-hemolytic streptococci, GABHS) is one of the important bacterial pathogens in clinical microbiology. It often causes upper respiratory tract infections such as tonsillitis, pharyngitis, and laryngitis. also leads to complications acute rheumatic fever post-streptococcal glomerulonephritis. Early diagnosis treatment these will prevent suppurative non-suppurative complications, transmission infection other people, chronic carriage. Today, streptococcal relies entirely on chemotherapy. Beta hemolytic group streptococci generally beta-hemolytic groups B (GBBHS), C, G are sensitive many chemotherapeutics, especially Penicillin Erythromycin. In patients with penicillin allergy, erythromycin, amoxicillin-clavulanate, or oral cephalosporins used instead penicillin. However, it has recently been understood that there strains resistant Erythromycin GABHS increasing. this study, situation our region resistance, which an alternative for people allergic infections, was investigated.
 Material Method: throat swab samples were taken from 150 pharyngitis 94 obtained by applying Bacitracin-SXT test culture method, antibiotic susceptibility tests performed Kirby-Bauer agar disc diffusion method. 
 Result: found susceptible Bacitracin SXT. GBBHS SXT.
 Conclusion: Erythromycin’s resistance be 19.1%. observed increased over years when compared previous studies. should not empirically treatment. An selected according results antibiogram test.